Complete the indicated task to unlock the achievement.
Achievement | How to unlock
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| - Unlock every other achievement
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| - (no official description)
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| - Complete Arena as Elizabeth
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| - Complete Arena as Lucretia
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| - Complete ending 4 with clean mind all the time
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| - Kill all bosses in episode 1
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- Doctor's Black Market Treasure
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| - Kill all bosses in episode 3
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- Everything Is Clearer Now 1
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- Everything Is Clearer Now 2
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- Everything Is Clearer Now 3
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| - (no official description)
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| - Collect 5 health bonuses in one game
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| - Have only 1 heart container
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| - Complete episode 1 without collecting hearts and healing herbs
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| - Complete episode 2 without collecting hearts and healing herbs
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| - Complete episode 3 without collecting hearts and healing herbs
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| - Complete episode 4 without collecting hearts and healing herbs
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| - Kill Green Viper (Secret)
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| - (no official description)
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| - Kill Liquid Sisters (Secret)
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| - (no official description)
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| - Kill Manless Face (Secret)
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| - Kill Manless Face as Amelia
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| - (no official description)
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| - Kill all bosses in episode 4
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| - (no official description)
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| - Manless Face (Elizabeth)25
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| - Kill all bosses in episode 2
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| - (no official description)
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| - Buy 5 items in one playthrough
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| - Kill Sinister Mask (Secret)
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| - (no official description)
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| - Kill the fat man (Secret)
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