| Trophy | How to unlock | Type
|
|---|
- All Are Lost Who Enter Here (secret)
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| - Enter the Fortress of Koth.
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| - Kill a boss while under the effects of a Hot Blood potion.
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| - Have 20 or more organs at one time.
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| - Find at least 140 unique items.
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| - Unlock all other trophies.
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| - Unlock at least 70 bestiary entries.
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| - Play the game for a combined total of 24 hours.
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| - Gamble with the Merchant as Scar.
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| - Escape a level after time has run out.
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| - Beat the game without picking up a weapon item.
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| - Collect three eye organs as the Eye.
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| - Turn into a Demon as the Priest.
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| - Find 500 gold in one run.
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| - Kill a boss while under the effects of an Introspection potion.
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| | |
| - Beat the game without picking up a grimoire item.
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| - Beat a level without taking damage.
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| - Beat the game without taking damage.
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| - Beat the game as the Skeleton King.
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| - Finish a boss fight with only one health remaining.
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| | |
| - Die in the first minute of gameplay.
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| - Unlock all playable characters.
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| - Beat the game at maximum Desecration.
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| - Drink 10 potions as the Scientist.
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| - Resurrect 30 or more enemies with a single Awaken potion.
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| - Find and equip 5 different grimoires in a single game as the Seeker.
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| - Beat the game as the Embalmer.
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| - Beat the game twice sequentially.
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- The End of All Things (secret)
| | |
| - Teleport 20 times in one game as the Starcreep.
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| - Die at Depth 1 as the Embalmer.
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- Touch the Demon Inside Me
| - Find a Demon or Horror aspect stone.
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| - Punch the final boss as the Brawler.
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| - Kill an Elite enemy after time runs out in a level.
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