| Achievement | How to unlock
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| - Produce 10,000 medicine boxes.
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| - Make 100,000 people be killed by your disease.
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| - Build 25 buildings in a single game.
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| - Research 10 technologies in a single game.
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| - Make 1,000 people be killed by your disease.
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| - Make a million people be killed by your disease.
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| - Research 50 technologies in a single game.
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| - Build 50 buildings in a single game.
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| - Produce a million medicine boxes.
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- Freaking High Risk Disease!
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| - Produce 100,000 medicine boxes.
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| - Hire 50 workers in a single game.
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| - Make a million coins in a single game.
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| - Hire 25 workers in a single game.
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| - Make 10 people be killed by your disease.
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| - Make 100 people be killed by your disease.
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| - Make 10,000 coins in a single game.
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| - Build 100 buildings in a single game.
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| - Research 100 technologies in a single game.
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| - Produce 1,000 medicine boxes.
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| - Hire a worker for your staff.
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| - Build 10 buildings in a single game.
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| - Produce 100 medicine boxes.
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| - Hire 10 workers in a single game.
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| - Make 10,000 people be killed by your disease.
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| - Complete The Combo Realizer scenario.
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- The Enthusiast Researcher
| - Complete The Enthusiast Researcher scenario.
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| - Complete The Evildoer scenario.
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| - Complete The Good Scientist scenario.
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| - Make 100,000 coins in a single game.
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| - Complete The Newbie Pharmacist scenario.
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| - Complete The Startup Capitalist scenario.
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| - Complete The Tycoon scenario.
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| - Produce 10 medicine boxes.
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