| Achievement | How to unlock
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| - Get a win with the Auto Rifle on Nightmare difficulty.
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| - Get a win with the Auto Rifle on any difficulty.
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| - Get a win with the Auto Shotgun on Nightmare difficulty.
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| - Get a win with the Auto Shotgun on any difficulty.
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| - Make 100 purchases at shops in a single run.
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| - Get a win with the Blade Launcher on Nightmare difficulty.
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| - Get a win with the Blade Launcher on any difficulty.
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| - Get a win with the Burst Pistol on Nightmare difficulty.
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| - Get a win with the Burst Pistol on any difficulty.
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- Cluster Launcher Master II
| - Get a win with the Cluster Launcher on Nightmare difficulty.
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- Cluster Launcher Master I
| - Get a win with the Cluster Launcher on any difficulty.
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| - Get five wins total on Nightmare difficulty.
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| - Get a win on Nightmare difficulty.
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| - Get a win on any difficulty.
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| - Get a win with the Crossbow on Nightmare difficulty.
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| - Get a win with the Crossbow on any difficulty.
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| - Get a win with the Dual Pistols on Nightmare difficulty.
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| - Get a win with the Dual Pistols on any difficulty.
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| - Get a win with the Dual Shotguns on Nightmare difficulty.
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| - Get a win with the Dual Shotguns on any difficulty.
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| - Defeat a boss in under ten seconds.
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| - Get a win on Normal difficulty without taking any damage.
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| - Clear the first biome on Nightmare difficulty without taking any damage.
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| - Defeat a boss without taking any damage.
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| - Defeat an elite without taking any damage.
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| - Get a win on Normal difficulty with five or less shop purchases.
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| - Defeat a boss with at least five greed perks in your inventory.
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| - Get a win with all weapons in the game.
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| - Get a win after looping at least once.
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| - Survive until island 100.
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| - Get five wins in a row on Nightmare difficulty.
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| - Fill all mod and perk slots in your inventory during a single run.
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| - Get a win with over 1M unspent crystals in your inventory.
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| - Get a win with the Minigun on Nightmare difficulty.
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| - Get a win with the Minigun on any difficulty.
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| - Get a win with the Orb Launcher on Nightmare difficulty.
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| - Get a win with the Orb Launcher on any difficulty.
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| - Level up a mod or perk to level 20 in a single run.
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| - Get two wins in a row on Nightmare difficulty.
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| - Salvage 100 pickups in a single run.
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- Rocket Launcher Master II
| - Get a win with the Rocket Launcher on Nightmare difficulty.
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| - Get a win with the Rocket Launcher on any difficulty.
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| - Reroll shops 50 times in a single run.
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| - Get three wins in a row on any difficulty.
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| - Get a win without firing your weapon.
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| - Get a win with the Sniper on Nightmare difficulty.
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| - Get a win with the Sniper on any difficulty.
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| - Fill 20 weapon mod slots with legendary weapon mods.
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| - Clear island 100 in 70 minutes or less.
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| - Clear island 50 in 40 minutes or less.
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| - Clear island 20 in 16 minutes or less.
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| - Get 10000 max health on a single run.
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| - Deal over 100K damage in a single shot.
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| - Get a win with over 7500 eliminations.
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| - Destroy 25 totems in a single run.
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