| Achievement | How to unlock
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| Ace (30 points) | Beat a boss without taking damage.
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| Annoying Customer (10 points) | Annoy the Crow at least three times during the same trip to the shop.
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| Another Little Piece of my Heart (20 points) | Trade in all your HP at heart machine.
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| Berserker (50 points) | Reach a max. HP of 15.
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| Best Friend (20 points) | Revive a player in co-op.
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| Collector (70 points) | Collect every single weapon.
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| Crux of the Matter (40 points) | Kill Crux.
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| Death from Beyond the Grave (10 points) | Get killed by a ghost.
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| Deceptive Mind (50 points) | Pick up at least 25 artifacts before looping.
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| Déjà vu (80 points) | Loop once.
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| Enormous Maggot (50 points) | Kill Larva.
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| Explorer (20 points) | Find a secret level.
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| Hard Shell (80 points) | Complete the game with the Egg.
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| Hunter (30 points) | Kill every enemy at least once.
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| Indy, is That You? (10 points) | Open a chest.
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| Level 10 Greed (70 points) | Collect enough artifacts to reach a risk value of 10.
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| Little Friend (60 points) | Kill Evil Teal.
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| Loop the Loop (100 points) | Loop twice.
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| Mud Monster (40 points) | Kill Muck.
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| Red Blob (30 points) | Kill Bogy.
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| Shopping Spree (30 points) | Buy three weapons during the same trip to the shop.
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| Slimy Salamander (20 points) | Kill Newt.
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| The Right Way is the Hard Way (60 points) | Beat the game without collecting any artifacts.
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| Thief (10 points) | Steal a weapon.
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| This is Not an Arcade (10 points) | Use a coin machine at least once.
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