| Effect | Code
|
|---|
| All floors have the basement room tile set | BASE MENT
|
| All items except troll bombs mimic Issac's movement | KEEP AWAY
|
| Alternate Hard mode | HARD HARD
|
| Analog television display | BOOB TOOB
|
| Eligible enemies become champions | CHAMP1ON
|
| Invisible enemies | BL1N DEYE
|
| Isaac and tears turn black | PTCH BLCK
|
| Isaac destroys rocks | NFB8 3WSG
|
| Isaac is grey | KAPP A
|
| Isaac leaves feces trail | BRWN SNKE
|
| Isaac only visible as brown shadow | CAMO K1DD
|
| Jumbled in-game text | DYSL EXIC
|
| Load screen always displays "Are You Sure You Want Me To Die?" | 1TEN DSHE
|
| Reversed controls | DRAW KCAB
|
| Slow motion while Isaac is idle | SLOW 4ME2
|
| Sound effects replaced with farts | FART SNDS
|
| Take damage when idle | D0NT ST0P
|
| Trophy | How to unlock
|
|---|
| A Blank Card (Bronze) | Kill Isaac with Eden.
|
| A Fetus In A Jar (Bronze) | Kill Mom's Heart 9 times.
|
| A Quarter (Bronze) | Kill Mom's Heart 8 times.
|
| Azazel (Bronze) | Make 3 deals with the devil in one run.
|
| Basement Boy (Bronze) | Beat the Basement/Cellar without taking damage.
|
| Blood Rights (Bronze) | Kill Satan with Samson.
|
| Bloody Lust (Bronze) | Kill Isaac with Samson.
|
| Blue Baby (Bronze) | Kill Mom's Heart 10 times.
|
| Boss Rush (Silver) | Beat the Boss Rush.
|
| Broken Ankh (Bronze) | Kill Satan with Lazarus.
|
| Cain (Bronze) | Hold 55 or more pennies at one time.
|
| Challenges (Bronze) | Beat all 20 Challenges.
|
| Daemon's Tail (Bronze) | Kill Satan with Azazel.
|
| Dark Boy (Bronze) | Beat the Depths/Necropolis without taking damage.
|
| Dark Room (Bronze) | Beat the Dark Room.
|
| Dead Boy (Bronze) | Beat the Chest or Dark Room without taking damage.
|
| Eden (Bronze) | Beat the Womb for the first time.
|
| Eve (Bronze) | Beat 2 levels in a row without picking up any hearts.
|
| Eve's Bird Foot (Bronze) | Kill Isaac with Eve.
|
| Everything Is Terrible (Bronze) | Kill Mom's Heart 5 times.
|
| Forget Me Now (Bronze) | Kill Satan with ...
|
| Golden God (Silver) | You are the best!
|
| Guardian Angel (Bronze) | Kill Satan with Maggy.
|
| Isaac's Heart (Bronze) | Kill Isaac with The Lost.
|
| Isaac's Tears (Bronze) | Kill Isaac with Isaac.
|
| It Lives (Bronze) | Kill Mom's Heart 11 times.
|
| Judas (Bronze) | Kill Satan.
|
| Judas' Tongue (Bronze) | Kill Satan with Judas.
|
| Lazarus (Bronze) | Have 4 or more soul hearts at one time.
|
| Lazarus' Rags (Bronze) | Kill Isaac with Lazarus.
|
| Little Baggy (Bronze) | Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment, or Speed Ball.
|
| Lost Poster (Bronze) | Beat the Dark Room with Isaac.
|
| Magdalene (Bronze) | Have 7 or more max red hearts at one time.
|
| Mama's Boy (Bronze) | Beat the Womb/Utero without taking damage.
|
| Mom's Knife (Bronze) | Kill Satan with Isaac.
|
| Platinum (Platinum) | Obtain all trophies.
|
| Platinum God (Gold) | Collect all items and unlock all secrets and endings.
|
| Real Platinum God (Gold) | 100% the game.
|
| Samson (Bronze) | Beat 2 levels in a row without taking damage.
|
| Something Cute (Bronze) | Beat the Caves 30 times.
|
| Something from the future (Bronze) | Beat the Basement 40 times.
|
| Something sticky (Bronze) | Beat the Depths 20 times.
|
| Spelunker Boy (Bronze) | Beat the Caves/Catacombs without taking damage.
|
| The Bomb Bag (Bronze) | Kill Satan with Cain.
|
| The Book Of Secrets (Bronze) | Kill Satan with Eden.
|
| The Book Of Sin (Bronze) | Kill all 7 sins.
|
| The Chest (Bronze) | Beat the Chest.
|
| The Coin Bag (Bronze) | Kill Isaac with Cain.
|
| The Guillotine (Bronze) | Kill Isaac with Judas.
|
| The Halo (Bronze) | Kill Mom using the Bible.
|
| The Lost (Bronze) | Finish the game's final secret.
|
| The Mind (Bronze) | Kill Satan with The Lost.
|
| The Negative (Bronze) | Beat Sheol 5 times.
|
| The Polaroid (Bronze) | Beat Cathedral 5 times.
|
| The Razor (Bronze) | Kill Satan with Eve.
|
| The Relic (Bronze) | Kill Isaac with Maggy.
|
| The Satanic Bible (Bronze) | Kill Isaac with Azazel.
|
| The Womb (Bronze) | Kill Mom.
|
| Transcendence (Bronze) | Kill Mom's Heart 3 times.
|