| Trophy | How to unlock
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| A House Divided (Bronze) | Hack a geth collective.
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| Against All Odds (Silver) | Survive the suicide mission.
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| Agent (Bronze) | Complete 5 missions discovered by scanning unexplored worlds.
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| Battlemaster (Bronze) | Gain the loyalty of the krogan.
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| Big Game Hunter (Bronze) | Thresher Maw defeated.
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| Brawler (Bronze) | Shoot and kill 20 enemies while they're knocked back by a punch.
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| Broke, Blind and Bedlam (Bronze) | Gain the loyalty of the thief.
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| Cat's in the Cradle (Bronze) | Gain the loyalty of the Assassin.
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| Catharsis (Bronze) | Gain the loyalty of the biotic Convict.
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| Colony Defense (Bronze) | Defend a human colony from attack.
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| Data Hound (Bronze) | Collect 6 Cerberus data packets scattered across Aite.
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| Digital Exorcist (Bronze) | Successfully shut down the rogue VI in Project Overlord.
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| Doppelganger (Bronze) | Help the Justicar resolve her mission.
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| Explorer (Bronze) | Visit 100% of the planets in an unexplored cluster.
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| Fade Away (Bronze) | Gain the loyalty of Archangel.
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| Fashionista (Bronze) | Personalize your armor.
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| Friend or Foe (Bronze) | Obtain geth technology.
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| Ghost Ship (Bronze) | Complete the investigation of a derelict alien vessel.
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| Ghost of the Father (Bronze) | Gain the loyalty of the Cerberus Operative.
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| Head Hunter (Bronze) | Perform 30 headshot kills with any weapon on humanoid targets.
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| Heart of Darkness (Silver) | Confront the Shadow Broker.
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| Highly Trained (Bronze) | View all advanced combat training videos at Shepard's private terminal.
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| Incineration Specialist (Bronze) | Incinerate the armor of 25 enemies.
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| Insanity (Gold) | Complete the game in the 'Insanity' difficulty level without changing the setting.
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| Long Service Medal (Silver) | Complete Mass Effect 2 twice, or experience the interactive backstory (Cerberus Pack downloadable content) and complete Mass Effect 2.
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| Master at Arms (Bronze) | Kill enemies with 5 different heavy weapons during the game.
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| Merciless (Bronze) | Make 20 enemies scream as they fall or are set on fire.
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| Missing in Action (Bronze) | Save your crew from an overwhelming attack.
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| Mission Accomplished (Silver) | Save humanity throughout the galaxy from certain annihilation.
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| N7 Elite (Platinum) | Acquire all trophies.
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| No One Left Behind (Gold) | Keep your team alive through the suicide mission.
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| Operative (Bronze) | Complete a mission discovered by scanning an unexplored world.
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| Overload Specialist (Bronze) | Disrupt the shields of 25 enemies.
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| Paramour (Silver) | Successfully pursue a relationship with a teammate.
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| Power Full (Bronze) | Evolve any power.
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| Power Gamer (Silver) | Reach Level 30 with one character.
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| Prospector (Bronze) | Retrieve mineral resources by scanning and probing a planet in the galaxy map.
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| Scholar (Bronze) | Unlock 15 new Mass Effect 2 codex entries.
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| Scientist (Bronze) | Complete any research project in the Normandy's laboratory.
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| Suicide Mission (Bronze) | Use the Omega 4 Relay.
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| Tactician (Bronze) | Hit 20 different targets with multiple biotic powers to combine the effects.
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| Technician (Bronze) | Obtain 10 technology upgrades.
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| The Archangel (Bronze) | Successfully recruit Archangel.
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| The Assassin (Bronze) | Successfully recruit the Assassin.
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| The Convict (Bronze) | Successfully recruit the biotic Convict.
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| The Cure (Bronze) | Gain the loyalty of the Professor.
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| The Justicar (Bronze) | Successfully recruit the Justicar.
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| The Krogan (Bronze) | Successfully recruit the Krogan.
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| The Prodigal (Bronze) | Gain the loyalty of the Cerberus Officer.
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| The Professor (Bronze) | Successfully recruit the Professor.
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| The Quarian (Bronze) | Successfully recruit the Quarian.
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| Treason (Bronze) | Gain the loyalty of the quarian.
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| Very Elusive (Bronze) | Return to active duty.
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| Warp Specialist (Bronze) | Warp the barriers of 25 enemies.
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| Weapon Specialist (Bronze) | Fully upgrade a weapon.
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