Destroy All Humans!

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All upgrades

Pause game play, then hold L2 and press Square, Circle, Left(2), Circle, Square while on the Mothership. All upgrades for the currently unlocked weapons will be available for purchase from Pox's lab.

Better DNA value

Every chance you get, do not kill the human before you extract their brain stem. Extract their brain stem first as it will make the DNA worth more (25 instead of 10).The easiest humans to do this to are the scientists in the level with glowing cows. For some reason, if the person that is important to you dies (the person you need to abduct), extract their brain stem before you return to the Mothership -- the DNA is usually worth more.

Brains

On the mother ship hold L2 and press R1, R1, R2, R2, Left, Right, Left, Right, R2, R1. This gives you extra DNA.

Cars Blow Up Faster

Shoot the tires of any vehicle with the zap-o-matic instead of the main vehicle body and their health goes down faster.

Faster Destruction In The Ufo

Instead of holding R to destroy buildings or large objects, tap R1 and the destruction will happen faster without waiting for the recharge.

Finding More Probes

Probes are necessary to get upgrades faster. In order to find them all, make sure to look high up on rocks or hard to reach places. Your jetpack is essential in getting to the high places. You may have to get up on the ledge or building, then use your jetpack to fly higher to get the probe.

Getting Away From The Law

Forget running away from the authorities with short legs. Use your jetpack liberally to fly away. Press Left Analog-stick Forward and hold X to boost away.

Holobob

Put your target (dot in the middle of the screen) on any human, and press Circle. In order to maintain your HoloBob, you must read the thoughts of the humans walking around. You can read the same person's thoughts repeatedly to keep your mental powers charged.

HoloBob

Put your target (dot in the middle of the screen) on any human, and press Circle. In order to maintain your HoloBob, you must read the thoughts of the humans walking around. You can read the same person's thoughts repeatedly to keep your mental powers charged.

Levitation death

It you levitate a person for a long time, they will die.

Lower brain juice meter

When you are in the form of another person, to make you brain juice meter go down, read other people's thoughts.

Moonwalk

Stand in an open area on any level and walk forward. Keep decreasing your speed until you eventually begin walking in place.

More DNA from Brain Extractions

To gain additional DNA from Brain Extractions, complete all of the main missions.Example: Instead of gaining 10 DNA, you will gain 15 DNA.

Password to Barge

The Password you say to the ferryman to get him to move the barge is Marlyn.

Screensaver

Allow the game to idle. Eventually the screen will turn black and white and elevator music will play in the background.

Staying human

After getting out of your UFO, aim at a human and press Circle. When you have changed into the human, the bar on the top left corner of the screen will go down. When it is all gone, you will change back into an alien. If you want to remain human, turn into a human and while walking around, scan other humans or animals to make the bar on the top left corner stay up.

Unlock Art of the Furon

Collect all Probes in Santa Modesta.

Unlock Blue Book: Saucer Blueprints

Collect all Probes in Rockwell.

Unlock Crypto, phone home!

Complete Attack of the 50ft president.

Unlock Developer Darwinism: Evolution of the game

Complete Attack of the 50ft president.

Unlock E3 Booth Footage

Complete Attack of the 50ft president.

Unlock Evolution of an Alien

Collect all Probes in Turnipseed Farm.

Unlock Face of the Enemy

Collect all Probes in Area-42.

Unlock Furon Down!

Complete Furon Down!

Unlock Goofy screenshots and voice overs

Complete Attack of the 50ft president.

Unlock Outro Movie

Complete Attack of the 50ft President.

Unlock Pathetic Humans !

Collect all Probes in Union Town.

Unlock Plan 9 from Outer Space

Complete Teenage Zombies from Outer Space.

Unlock Teenagers from Outer Space

Complete Attack of the 50ft President.

Unlock The Concept Barnyard

Collect all Probes in Capitol City.

Various Codes

Hold L2, enter cheat, then release L2.

Invinciblity
Square, circle, left of d-pad, left on d-pad, circle, square

Infinite Ammo
left on d-pad, circle, R2, right on d-pad, R1, square

Infinite Mind
R1, R2, circle, right on d-pad, R2, circle

Aware Like A Fox
Right, Square, R2, R1, Right, R2

Nobody Loves You
Right, R2, R1, Square, Right

Mmmm Brains! (Must be entered on Mothership)
R1, R1, R2, R2, Left, Right, Left, Right, R2

More Upgrades (Must be entered on Mothership)
Square, Circle, Left, Left, Circle, Square