| Achievement | How to unlock
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| Brawler | Deal 10,000 damage with melee weapons.
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| Bruiser | Deal 100,000 damage with melee weapons.
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| Doctor | Heal 10,000 health.
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| Gunner | Deal 25,000 damage with ranged weapons.
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| Inventor | Deal 1,000,000 damage with minions.
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| Mad Scientist | Deal 10,000,000 damage with minions.
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| Marksman | Deal 250,000 damage with ranged weapons.
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| Med Student | Heal 1,000 health.
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| Medic | Heal 2,500 health.
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| Sharpshooter | Deal 1,000,000 damage with ranged weapons.
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| Tank | Deal 500,000 damage with melee weapons.
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| Tinkerer | Deal 50,000 damage with minions.
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| Victories #1 | Win 1 game on Casual or Hard difficulty.
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| Victories #2 | Win 5 games on Casual or Hard difficulty.
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| Victories #3 | Win 10 games on Casual or Hard difficulty.
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| Wave 20 | Survive through wave 20 in infinite mode.
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| Wave 25 | Survive through wave 25 in infinite mode.
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| Wave 30 | Survive through wave 30 in infinite mode.
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