| Achievement | How to unlock
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| Create the Fish | Complete the Fish creature.
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| Create the Jellyfish | Complete the Jellyfish creature.
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| Create the Nautilus | Complete the Nautilus creature.
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| Create the Planarian | Complete the Planarian creature.
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| Create the Rotifer | Complete the Rotifer creature.
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| Create the Shrimp | Complete the Shrimp creature.
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| Create the Trilobite | Complete the Trilobite creature.
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| Create the Volvox | Complete the Volvox creature.
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| Create the Worm | Complete the Worm creature.
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| Divinity | Give life to 1000 Trimoebas.
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| Evolution | Complete all the creatures.
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| Fair barter | Complete barter in two different ways.
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| First climb | Meet the purple Trimoeba.
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| First mutation | Discover the mutant Trimoeba.
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| Hiroshima | Detonate 1000 Trimoebas.
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| Lord of Mitochondria | Complete half game in advanced mod.
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| Lord of Trimoebas | Complete the game in advanced mod.
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| Lord of the Volvox | Complete the Volvox in advanced mod.
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| Manholes | Complete Drainage in three different ways.
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| Patriarch | Clone 1000 Trimoebas.
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| Sailor | Complete Node in two different ways.
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| Secret fish | Complete Fishbone without freeing the stucked trimoeba.
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| Sleeve | Complete Longarm without pasting any hooked Trimoeba.
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| Stylist | Try all other 15 background molds and comple a level for each of them.
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| Two headed beast | Complete Sleeping Beast in two different ways.
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