| Achievement | How to unlock
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| Antitoxin | Clear the elevator shaft of the bio-material.
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| Archivist | Find every Audio Log.
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| Backdoor attack | Reprogram the three Simulation Units on the Command Deck.
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| Bigger is better! | Reach Level 6 Heavy Weapons skill.
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| Captain | Complete the game as a Marine.
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| Chop suey | Kill an enemy with the Laser Rapier.
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| Custom Firmware | Reach Level 6 Modify skill.
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| Cybernetic Grace | Unlock all Achievements.
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| Cyberpunk | Reach Level 6 Cyber Affinity.
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| Deus Ex Machina | Complete the game from start to finish on Impossible difficulty.
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| Egg Hunt | Destroy all sixteen Black Eggs.
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| Expanding your mind | Choose the OSA career path.
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| Finding your sea legs | Choose the Navy career path.
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| Fire and forget | Kill an enemy using the Annelid Launcher.
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| Free your mind | Reach Level 6 Psionics.
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| Hard Reboot | Restart the Engine Core on the Engineering Deck.
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| How extraordinary | Reach Level 6 Exotic Weapons skill.
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| I can take it | Reach Level 6 Endurance.
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| I have the power! | Recharge an energy-based item or weapon with Electron Cascade.
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| I look after my things | Reach Level 6 Maintain skill.
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| I want you! | Choose the Marines career path.
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| I'm a lover... | Visit every one of the Love Simulation rooms.
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| Into the guts | Reach the Engineering Deck through the Medical maintenance access.
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| It takes two to tango | Hack a turret while the security is not offline.
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| Join us? | Receive the secret e-mail.
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| Little Rebellion | Disobey orders.
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| Lock and Load! | Reach Level 6 Standard Weapons skill.
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| Look at you | Reach Level 6 Hack skill.
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| Mastermind | Complete the game as an OSA Agent.
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| Mind Blowing | Destroy the Brain of the Many.
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| Mr. Fix it | Reach Level 6 Repair skill.
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| Overkill | Kill an enemy using a Level 2 modified Fusion Cannon's Death Mode.
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| Power up with a paper clip | Hack a GAMEPIG Handheld game console.
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| Powered up! | Reach Level 6 Energy Weapons skill.
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| Primary Data Loop Compromised | Weaken Xerxes.
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| Quicksilver | Reach Level 6 Agility.
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| Redirected | Use Kinetic Redirection to pull an out-of-reach item.
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| Remote control | Hack psionically using the 4th tier Remote Circuitry Manipulation power.
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| Service Pack | Apply four OS upgrades.
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| Strange bedfellows | Using Imposed Neural Restructuring, make an enemy kill another enemy.
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| Striker | Complete the game as a Navyman.
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| Strongman | Reach Level 6 Strength.
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| Stunning | Kill an enemy that is stunned with the Stasis Field Generator.
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| The right tool for the job | Kill a robot with the Armor-Piercing rounds.
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| To the max! | Upgrade any weapon to Level 2 Modification.
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| Unsigned code | Turn the security system off after alerting The Many to your presence.
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| Vampiric tendencies | Drain a non-robotic target of health using the 5th tier Soma Transference power.
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| Welcome aboard, soldier | Make it out of Cryo Recovery B and into Medical.
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| Where's my microscope? | Reach Level 6 Research skill.
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| You can't see me | Kill an enemy while using 4th tier Photonic Redirection power.
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