| Achievement | How to unlock
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| A Different Side of Yu | You scanned your Phantom Shift duplicate with the Psychoscope.
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| A Friend in Need | You recovered Mikhaila's booster shots and healed her.
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| Abandon Ship | You fled Talos I aboard Alex's escape pod before completing your mission.
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| Adrift | You rescued Dr. Igwe from a cargo container.
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| Awkward Ride Home | You escaped Talos I aboard Dahl's shuttle with only Dahl.
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| Ball Lightning | You used Electrostatic Burst to drop two or more Operators at once.
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| Best Served Cold | You killed Luka and avenged Abby.
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| Black Market | You found all the smuggler's dead drops.
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| Brain Trust | You helped Igwe, January, and Mikhaila meet in your office.
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| Coffee Break | You found Dr. Calvino's secret stash.
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| Cold Dead Hands | You fully upgraded a weapon.
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| Dead Calm | You killed an enemy while using Combat Focus.
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| Dear Future Self | You found and listened to all the messages you left for yourself.
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| Deprogramming | You used Mindjack to free a mind-controlled Human.
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| Do No Harm | You completed the game without killing any Humans.
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| Engineer | You repaired (20) objects on and around Talos I.
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| Escape Velocity | You blasted yourself as an object for at least 20 meters while in normal gravity.
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| Facsimile | You met January for the first time.
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| Gift to the World | You found Gustaf Leitner's Connectome for Dr. Igwe.
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| I and It | You killed every Human on and around Talos I.
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| I and Thou | You completed the game in the most empathetic way possible.
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| Intrinsic Value | You recycled yourself.
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| It's Alive! | You created a Phantom using Phantom Genesis.
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| Know Thine Enemy | You acquired a Typhon power.
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| Know Thy Self | You acquired a Human ability.
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| Makeup Exam | You returned to the Simulation Lab and completed the tests in Rooms A, B, and C.
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| Mimesis | You mimicked a Mimic.
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| Mimic Massacre | You killed (5) Mimics in 5 seconds.
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| Missing Persons | You located all employees on Talos I.
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| No Needles | You completed the game without ever acquiring any Typhon power or Human ability.
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| No Show | You died to helicopter blades on your first day on the job.
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| Open Says She | You used Danielle's voice samples to access Deep Storage.
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| Operator | You hacked at least (20) hackable objects on and around Talos I.
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| Press Sneak | You read all the e-mails on Talos I.
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| Prism Master | You read the entire Starbender series and don't regret it.
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| Psychometry | You found and listened to all TranScribe recordings.
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| Push the Fat Guy | You killed Alex.
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| Reduce, Reuse, Recycle | You used a single Recycler Charge to recycle at least 20 objects.
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| Self-Incriminating | You found out what happened to Mikhaila's father and let her know.
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| Shapeshifter | You mimicked (20) or more unique objects.
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| Split Affinity | You completed the game once acquiring only Typhon Powers and again acquiring only Human abilities.
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| Suicide by Proxy | You killed January.
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| Tee One Up | You killed an enemy while they were Lifted.
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| The Gates of Hell | You completed the Shipping and Receiving objective and no human lives were lost.
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| This Never Happened | You performed an apto-regressive neurotomy on Dahl.
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| Thoughts Can Kill | You used Psychoshock on a Human.
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| TranStar Gourmand | You consumed one of every type of food and drink on Talos I.
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| You Rang? | You used the Psychotronics satellite to dismiss or summon the Typhon Nightmare.
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