| Achievement | How to unlock
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|---|
| Alpha and Omega | Defeat the Creator.
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| Bibliophile | Collect all Character archives.
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| Champion | Beat Security Level 10 with J4X.
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| Child's Play | Clear a room in one turn.
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| Chill Out | Defeat the Freon.
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| Cluster Migraine | Defeat the Brains.
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| Commando | Unlock Security Level 5 with K31.
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| Contender | Unlock Security Level 10 with J4X.
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| Cyber Punk | Upgrade six cards in a single run.
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| Debunked | Defeat the Scientist.
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| Decked Out | Win a run with more than 50 cards in your deck.
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| Double Trouble | Defeat the Twins.
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| Fire Extinguisher | Defeat the Fire Warden.
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| Galaxy Brain | Win a run without gaining any patches other than the ones you start with.
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| Golden Goose | Collect $2000 or more in a single run.
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| Grand Master | Beat Security Level 10 with L33.
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| Hero | Rescue 100 Kids.
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| High Tech | Upgrade four patches in a single run.
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| It's Morbin' Time | Use four Infusions in one turn.
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| It's Over 9! | Spend 10 or more Energy in one turn.
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| Journeyman | Unlock Security Level 5 with J4X.
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| K.I.A. | Defeat the Commander.
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| Known Threat | Unlock Security with K31.
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| Legendary Assassin | Beat Security Level 10 with K31.
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| Master | Unlock Security Level 10 with L33.
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| Maxed Out | Obtain all starter cards and patches for L33, J4X and K31.
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| Mission Complete | Win a run.
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| Mission Impossible | Obtain all other achievements.
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| Mitts On | Unlock J4X.
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| Nitro Kid | Rescue 1 Kid.
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| Operator | Unlock Security Level 10 with K31.
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| Practitioner | Unlock Security Level 5 with L33.
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| Pyromaniac | Defeat the Feuer.
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| Quick Math | Play 20 or more cards in a single turn.
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| Rogue Runner | Win 5 runs.
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| Saviour | Rescue 250 Kids.
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| Skill Issue | Die on the Rooftop Floor.
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| Smooth Brain | Finish a turn without playing a card.
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| Student | Unlock Security with L33.
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| Target Practice | Unlock K31.
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| Terminator | Win a battle with 1 HP remaining.
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| Underdog | Unlock Security with J4X.
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| Untouchable | Defeat a boss without taking any damage.
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| Vegan | Win a run without using any Infusions.
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| Weed Wacker | Defeat the Vine Queen.
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| You're Fired | Defeat the Founder.
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