The Hand Of Jehuty is a teleport upgrade for your Prosthetic Arm. When you shoot someone with it, they will be teleported to your location, and you can use CQC to take them out silently. Even though the range is quite limited, it is a really fun tool to use and will keep your enemies wondering what just happened. It is perfect for taking out heavily armored enemies with a single hit (especially in multiplayer). You can also upgrade it to increase range and battery life. To unlock it, you must successfully complete Side Op 49: "Capture The Legenday Ibis". This side op only becomes available after completing story Mission 31. If it does not appear after Mission 31, it is because only a limited number of side ops can simultaneously be active per area. Just keep doing other side ops, and it will eventually appear. You must then develop the Hand Of Jehuty at Mother Base in your iDroid. Development requires 340,000 GMP, 120 Precious Metal, and your R&D Team must be Level 28 or higher.
Kojima Productions Lives
After you are rescued from your initial encounter with the Man on Fire in the prologue, you must follow someone down a corridor. There's a rail to your left, which lets you pull yourself from the floor. Look closely at the cork board on the wall to see a poster referencing Kojima Productions and inviting you to "Join the Fox Team." There's also a booth number: CP 2308. That booth that was assigned to Kojima Productions during GDC 2013.
Nuclear disarmament ending
Successfully complete Mission 31. All nuclear weapons at the FOBs of everyone in your game platform's region must be dismantled. To qualify, you must not own or have a nuclear weapon in development. You must dismantle any nuclear weapons in your arsenal. Additionally, all nuclear weapons on the regional server for your game platform must be dismantled so the total amount of nukes for your platform and region is zero. After all conditions are met, the hidden nuclear disarmament ending will appear after you return to Mother Base or after you complete a main mission. If new nukes are developed afterwards, the ending will not be available again until all the previous conditions are met.
Quiet Boss fight Trick
Quiet is a sniper and she will always be stationary waiting for a chance to get a hit on you. That being said, it's possible to order a supply drop on her position to stun her. After a few seconds she'll change her position. Ordering a supply drop on her new position for a second time will stun her completely and you'll have defeated her in two hits. This is also effective in completing all mission tasks for this mission.
Raiden costume
To get the secret Raiden suit, you must complete all story missions with an "S" rank (excluding duplicate missions with Extreme, Subsistence, and Total Stealth mods). Only the 38 unique missions and prologue must be completed with an "S" rank; the 12 duplicates can be ignored. This will then give you the "Grand Master Certificate (Elite)" key item, which allows you to develop the Raiden suit through your iDroid at Mother Base. Development requires 1,190,000 GMP, 70 Digitalis Purpurea, 20 Digitalis Lutea, and your R&D Team must be Level 53 or higher. The main strength of this outfit is the increased sprinting speed and jump distance, as well as the nice cosmetic look of the suit. It allows you to run at the speed of your horse. When you run into enemies, it will knock them down. Usage costs 8,400 GMP per deployment. It also comes with the following disadvantages: you cannot use your prosthetic arm, it cannot be used during FOB missions, and you are limited to an "A" rank when playing main missions. The suit is best used for open world exploration and side ops.
Recruiting D-Dog
Fulton extract the puppy at the start of Mission 4 (he is at the landing zone where you leave the helicopter). If you missed this, you can replay the mission. Alternately, he can be found at the landing zones of Mission 3 and 5. Return to Mother Base (either complete the mission or call back the helicopter to abort) to view a cutscene with the dog when you arrive at base. Then, successfully complete Missions 7, 8, 9, 10, and any other two missions of your choice. Next, return to Mother Base, and the puppy will be grown up; you will see a cutscene when you arrive. D-Dog will now be available as a buddy, and you will get the "Cry Havoc" achievement. Note: If he is not grown up yet, play a few more missions, and return later.
Recruiting Quiet
At the end of Mission 11, do not kill Quiet (in the cutscene where you hold the gun to her head). If you have killed her, you can replay the mission. Successfully complete Mission 14 to unlock Side Op 111: Visit Quiet. Visit her on the medical platform of Mother Base. When you arrive at the helipad, go down the stairs in front of you to find her cell. Then, call back the helicopter to leave the area to view a cutscene with Quiet. She will now be available as a buddy, and you will get the "Speechless" achievement.
Weapon customization
To unlock weapon customization, complete the following tasks:
1. Successfully complete Side Op 107: "Extract The Legendary Gunsmith". This side op mission becomes available after story Mission 13. It usually does not appear right away because there can only be a limited number of side ops per area at the same time. Thus, keep doing other side ops, especially in the Angola-Zaire Border region, until it appears.
2. Successfully complete Side Op 108: "Extract The Legendary Gunsmith Again". This side op mission should be triggered automatically after completing Side Op 107 (return to ACC, and it should be available). If it is not available, you must keep doing other side ops until it appears. It has also appear for some people after Side Ops 06 and 48 were completed.
Step 3: Successfully complete Side Op 109: "Extract The Legendary Gunsmith Yet Again". This is the last part of this quest line. It should appear after completing Side Op 108.
You can now customize weapons in the ACC from your iDroid. Go to the "Mother Base" - "Customize" - "Weapons" tab, and choose the type of weapon you want to create. To get new parts, you must develop more weapons. The parts of each developed weapon will be available for customization.
Wormhole Fulton Extraction Device
The Wormhole Fulton Extraction Device is a very useful upgrade. Other than the normal fulton, this one cannot be shot down, making it perfect for extracting enemies and their vehicles mid-combat. You can even use it in buildings or when there is something overhead, as it always has a 100% extraction chance. To unlock it, successfully complete Side Op 50: "Capture The Legenday Jackal", which only becomes available after completing story Mission 31. If it does not appear after Mission 31, it is because only a limited number of side ops can simultaneously be active per area. Just keep doing other side ops, and it will eventually appear. You must then develop the Wormhole Device at Mother Base in your iDroid. Development requires 850,000 GMP and your R&D Team + Support Unit must be Level 40 or higher. Everything you can extract with the normal fulton can also be extracted with the wormhole.