| Achievement | How to unlock
|
|---|
| Baby Boot Camp | Train 5 militia squads.
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| Big Boss | Hire 50 Mercenaries.
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| Big Boy Boot Camp | Train 25 militia squads.
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| Boom!!! | Destroy 10 environment pieces.
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| Cold-Blooded Killer | Kill 100 Enemies.
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| Dead Prince of San Hermanos | Kill the prince and complete the game.
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| Demo Guy | Destroy 50 environment pieces.
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| Demolition Man | Destroy 100 environment pieces.
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| First Strike | Complete the first mission.
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| Healer | Use 25 bandages.
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| Hireling | Hire 5 Mercenaries.
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| Killer | Kill 25 enemies.
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| Medic | Use 5 bandages.
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| Medicine Man | Use 50 bandages.
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| Mercenary Tryouts | Train 75 militia squads.
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| Money Man | Hire 15 Mercenaries.
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| Side Chef | Complete all side missions.
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| Side Dish | Complete a side mission.
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| Spicy Affair | Complete the Spice questline.
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| The Reaper | Kill 500 enemies.
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| This Is My House | Heal 100 mercenaries in doctor mode.
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| What's Up Doc? | Heal 50 mercenaries in doctor mode.
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| What, Who, Where? | Find a way to Angetta.
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| Who Called The Doctor? | Heal 5 mercenaries in doctor mode.
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