Defeat at least 100 opponents as Dante during the ending credits.
Bloody Palace mode
Successfully complete the game under any difficulty setting.
Cheat Mode
Note: This requires a game pad. Hold Button 5 + Button 6 + Button 7 + Button 8 + D-pad Up/Left + Left Analog-stick Down/Right until "Devil May Cry" is spoken at the starting menu. This will unlock all bonus modes, alternate costumes, and gallery entries.
Coatless Vergil
Complete Vergil story mode under the easy difficulty setting.
Dante Must Die Mode
Successfully complete the game as Dante or Vergil under the hard difficulty setting.
Easy difficulty
Intentionally fail a mission under the normal difficulty setting three to five times. A message will appear, stating that you have unlocked the easy difficulty level. Alternately, successfully complete the game under the normal difficulty setting.
Gallery items
Complete the game on Easy or higher to unlock Gallery mode. Complete the indicated task to unlock the corresponding item in the Gallery.
Bonus Art 1: Complete the game under the easy difficulty.
Bonus Art 10: Get an "S" rank on all missions in Dante Must Die!.
Bonus Art 11: Get an "SS" rank on all missions in Easy.
Bonus Art 12: Get an "SS" rank on all missions in Normal.
Bonus Art 13: Get an "SS" rank on all missions in Hard.
Bonus Art 14: Get an "SS" rank on all missions in Very Hard.
Bonus Art 15: Get an "SS" rank on all missions in Dante Must Die!.
Bonus Art 2: Complete the game on Normal.
Bonus Art 3: Complete the game on Hard.
Bonus Art 4: Complete the game on Very Hard.
Bonus Art 5: Complete the game on Dante Must Die!.
Bonus Art 6: Obtain an "S" rank on all missions in Easy.
Bonus Art 7: Obtain an "S" rank on all missions in Normal.
Bonus Art 8: Obtain an "S" rank on all missions in Hard.
Bonus Art 9: Obtain an "S" rank on all missions in Very Hard.
Concept Art, E3 Promotional Video, Crazy Gameplay Video: Complete the game on Easy or Normal.
Event Promotional Video, Devil May Cry 3 Original Demo: Complete the game on Very Hard.
Hi-Res CG Art, Kazuma Kaneko's Illustrations, Motion Capture Video, Video Storyboard: Complete the game on Hard.
Hard difficulty
Successfully complete the game under the normal difficulty setting.
Mission number references
During the introduction sequences to every mission, a number that corresponds to that mission can be found.
Mission 1: A big "1" on the pizza box.
Mission 2: A "2" on a billboard near the outside of Dante's shop.
Mission 3: Three enemies are burned by Lady's motorcycle and fall to make a "3".
Mission 4: There is a banner near where Vergil and Arkham are standing in the shape of a "4".
Mission 5: A bloodgoyle gets hit into a wall. The blood remaining on the wall is in the shape of a "5".
Mission 6: Lady blasts a rocket into the ground and the mark on the ground forms a "6".
Mission 7: After Lady shoots Dante in the head, he smears the blood on the wall. The blood runs into the shape of a "7".
Mission 8: When Dante gets up, goes near the pillar, and is about to jump off, you can see a faint shape of an "8" in the moon behind him.
Mission 9: One of Lady's spent shells falls on the ground. A "9" is on the bottom of the bullet.
Mission 10: When Vergil stabs Arkham the blood spatters Arkham's book in the form of a "10".
Mission 11: When Arkham disappears from where he was stabbed, the smeared blood leaves an "11" behind.
Mission 12: After Dante grabs the Haywire Neo-Generator, Jester escapes on something shaped like a "12".
Mission 13: Immediately after Vergil cuts his hand to make a sacrifice, the camera angle changes. While the angle is turning you can see a "13" carved into a pillar.
Mission 14: At the end of the intermission sequence, it shows an angle aiming down into the pit where Vergil fell. On the wall of the crevice is a carved "14".
Mission 15: After awhile after the intermission sequence starts, the camera will face a door with three symbols on it. Just to the right of it is a dried up plant. The branches are shaped into the number "15".
Mission 16: A little while after Dante starts changing between normal and demon forms he will take out his guns and shoot them at the same time. If you can spot it, the flash of the two gunshots makes "16". You must watch extremely carefully.
Mission 17: After Arkham pulls the force edge from the stone, the rocks shift around. In the bottom left of the screen will be two rock pillars next to each other. They form a "17".
Mission 18: As Dante is rising up the portal to the demon world, a single newspaper flies around the bottom right corner of the screen with an "18" on it.
Mission 19: The camera will start to turn at the beginning of the intermission sequence. As it is turning, there is a bookshelf. There is an area with books missing in the shape of a "19".
Mission 20: After Lady shoots her father and starts crying in the background, the mist forms the number "20".
Mundus reference
Complete the game and get the Vergil ending, where he falls down in the pool of blood. There will be three round and red electric orbs that he says he could defeat if his father did it. This is most likely Mundus, the last Boss from the first game, because Vergil obviously loses and succumbs to Mundus' power.
Sparda Costume (Vergil)
Successfully complete the game as Vergil under the hard difficulty setting to unlock a costume to make him appear as Sparda from the original Devil May Cry.
Super Dante
Successfully complete the game under the Dante Must Die difficulty setting to unlock Super Dante as a character. He has an unlimited Devil Trigger.
Super Vergil
Successfully complete Bloody Palace mode to unlock Super Vergil as a character. He has an unlimited Devil Trigger.
Vergil story mode
Successfully complete the game under any difficulty setting.
Very hard difficulty
Successfully complete the game under the hard difficulty setting.