| Achievement | How to unlock
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| Alien Tears | Earn a gold medal on all missions in the Story mode.
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| Annihilator | Kill 10,000 aliens.
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| Arsenal | Build 20 towers in one mission.
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| Base Defender | Complete the Story mode.
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| Boot Camp | Finish the first 3 missions.
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| Burn Baby Burn | Build 5 Inferno towers.
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| Close Call | Save a core less than 10 seconds away from the map exit.
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| Confident | Use speed up controls for a total of 30 seconds in any one mission.
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| Death From Above | Fire the orbital laser.
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| Diversity | Build all tower types in one mission.
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| Eradicator | Kill 100 aliens.
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| Exterminator | Destroy 1000 aliens.
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| Field Promotion | Earn at least one silver medal.
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| Filthy Rich | Win with 10,000 resources remaining.
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| Firebug | Beat an advanced mission with only Inferno towers.
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| First Blood | Kill 1 alien.
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| Flawless Victory | Earn at least one gold medal.
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| Full Defense | Build 50 towers in one mission.
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| Full House | Build all upgrades of all tower types in one mission.
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| Full Potential | Beat an advanced mission with only level 3 towers and no selling.
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| Great Ball of Fire | Build 5 Meteor towers.
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| Gun Crazy | Beat an advanced mission with only Gun towers.
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| Happy Returns | Recover a loose core.
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| Head Trauma | Build 5 Concussion towers.
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| Hey! That's mine! | Kill an alien carrying a power core.
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| High Voltage | Build 5 Tesla towers.
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| I Spy | Activate reconnaissance system.
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| Indecisive | Sell 10 towers in a single mission.
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| Kaboom! | Build 5 Cannon towers.
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| Leadhead | Build 5 Gun towers.
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| Liquidator | Sell 5 towers.
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| Master Strategist | Earn a gold medal on all Challenge modes.
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| Minimalist | Beat an advanced mission with only level 1 towers.
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| Nail Biter | Win mission with the last core less than 10 seconds away from the map exit.
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| No Sale | No towers sold in a single mission.
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| Not So Fast | Build 5 Temporal towers.
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| Overseer | Build 5 Command towers.
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| Penny Pincher | Win with 5,000 resources remaining.
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| Pew Pew | Build 5 Laser towers.
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| Planet Defender | Earn a silver medal on all missions in the Story mode.
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| Power Builder | Build 6 towers within 10 seconds.
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| Pyrrhic Victory | Shoot down flying alien carrying a core.
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| Relay Race | Witness 1 core handed off 10 times within 20 seconds.
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| Retry | Reload an earlier save checkpoint.
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| Salvage Rights | Destroy at least one boss alien.
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| Sharpshooter | Shoot down a flying alien.
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| Shell-shocked | Beat an advanced mission with only Cannon towers.
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| Siege Breaker | Survive 100 waves on the Grinder challenge mode.
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| Surplus | Win with 1,000 resources remaining.
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| The Long Road | Alien time until exit exceeds 5 minutes.
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| The Not-So-Friendly Skies | Build 5 Missile towers.
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| Tower Expert | Build every tower and upgrade.
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| Untouchable | Beat an advanced mission with zero cores captured.
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| Well Invested | Gain 10000 resources from interest in a single mission.
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| What IS that? | Inspect 10 aliens.
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| Xenocide | Kill 50,000 aliens.
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| Yellow | Beats Green Upgrade a tower.
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