Turn on your hunter's sense and try to stand back from the direction he hits you from first. You will see him come down from the mountain. Make sure you have your most powerful revolver out. Shoot when he comes out of the bush, Keep your hunter's sense on the entire time.
Grizzly bear
The first predator you encounter is the grizzly bear. The quickest way to kill it is to wait for it to stand on its hind legs. When its mouth opens, shoot it down the throat.
Lion
Take out the .416 rifle. When you first enter the "arena", move to the left. There should be a cave. Wait in front of it for the lion to charge. Just before it hits you, shoot it. Then very quickly jump into the cave. Go out the other end. Move straight for the lion. When you are close enough, it will turn around and swing at you. Shoot just as soon as it turns around. Note: You must keep running at the lion before and after you shoot it. By doing this, after you shoot it you will be close enough to the cave to jump back into it. Do this repeatedly until the lion dies.