| Achievement | How to unlock
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| All-in | Unlock all diseases in one system.
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| Athlete | Evolve the Athlete Lifestyle.
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| Better Doctor | Reach 100% Recovery while patient health is 60% or higher at lethal difficulty.
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| Bio Inc. Master | Complete all Death and Life stages at lethal difficulty.
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| Busy Labs | Perform 3 or more diagnostic tests simultaneously.
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| Circulatory Collapse | Have your victim's circulatory system collapse first.
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| Close Call | Win a game at 95% recovery or more.
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| Dean of Medicine | Complete all Life stages.
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| Dedicated Player | Complete all Death and Life stages.
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| Detective | Finish a stage with 200% Diagnosis efficiency or more.
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| Diagnostic Master | Identify 5 diseases or more using a single test.
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| Diagnostic Professional | Identify 3 diseases or more using a single test.
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| Digestive Collapse | Have your victim's digestive system collapse first.
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| Good Doctor | Reach 100% Recovery while patient health is 60% or higher.
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| Good Surgeon | Perform 4 or more operations in a single game.
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| Heart Attack | Evolve Heart Attack.
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| Heartbreaking Loss | Lose a patient at 90% Recovery or more.
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| Immune Collapse | Have your victim's Immune system collapse first.
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| It is Lupus | Diagnose Lupus.
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| It's Never Lupus | Evolve Lupus.
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| Last Resort | Reach 100% Recovery while patient health is 5% or below.
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| Lethal Walk In The Park | Win a game before the recovery reaches 70% at Lethal difficulty.
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| Loaded | Start a game with 5 boosters.
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| Loser | Lose a game.
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| Lupus Nephritis | Evolve Lupus Nephritis.
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| Medical Student | Complete at least one tutorial.
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| Muscular Collapse | Have your victim's muscular system collapse first.
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| Nervous Collapse | Have your victim's nervous system collapse first.
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| No Stress | Reach 100% recovery before patient is sent to emergency room.
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| Opportunist | Cause a Strike while in Emergency Room.
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| Perfect Lifestyle | Evolve 6 or more Lifestyles items.
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| Prescription Frenzy | Treat 3 or more diseases simultaneously.
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| Reaper | Complete all Death stages.
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| Renal Collapse | Have your victim's renal system collapse first.
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| Respiratory Collapse | Have your victim's respiratory system collapse first.
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| Richie Rich | Collect 250 Bio Points or more in a game.
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| Silent Killer | Evolve 6 or more diseases before the recovery has started.
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| Skeletal Collapse | Have your victim's skeletal system collapse first.
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| Stabilized | Use an intensive care operation or lifestyles to get your patient out of the emergency room.
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| Thrifty | Stack 30 Bio Points before spending anything.
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| Walk In The Park | Win a game before the recovery reaches 70%.
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