Finish the entire game with Leon on any difficlty and any rank.
Alternate uniforms
Start a new game with Leon and choose your settings to: red blood color and normal difficulty. Begin the game, and advance past the opening sequence. Do not pick up any items and try to avoid using your handgun bullets (you only really need them for the zombies in the bus and the zombie with the key - avoid the rest of the zombies). Get to the police station gate and go to the lower level stairwell. Outside you should see Brad Vickers (from Resident Evil 1 and 3) as a zombie. Use the rest of your clip on him. If he is still standing after that, run into the police station and get the handgun bullets on the desk near the computer, then go back outside and finish him off. Check his body to find a Special Key which will allow you to change clothes in the Dark Room (where you develop film). Leon has a leather jacket with skull emblem and an old S.T.A.R.S uniform with a baseball hat and Claire has a leather suit with a fast firing pistol called the Colt SAA. Another way to kill the zombie easily is to go up close and shoot his legs to make him fall forward, Then allow him bite your leg and you will crush his head. However, only do so if your condition is at Fine or Caution. If you get hurt by the zombie, get the herb in the garden at the top of the stairwell. This trick allows you to get the uniforms without completing either scenarios. The only difference is if you complete the game you see a short sequence that says "Do not pick up any items at the police station!".
Complete either character's first and second scenarios in less than three hours. A zombie in a uniform will appear after both missions are completed to confirm correct code entry. Load the saved game and begin the first scenario by going to the police station without collecting any items. Quickly move past the zombie that appears in the alley near the police station. Collect the shotgun, then kill the zombie. Take the special key from the zombie's body to open the lockers with alternate uniforms. Claire has a denim jacket, with a quick shooting revolver. Leon has two alternate uniforms (a leather jacket with skull emblem, or a tank top and baseball hat), one of which will allow him to shoot with one hand.
Dead Hunter
Unlock the room in the Lab which requires two people to enter. In the Culture Experiment Room is find a dead Hunter from the first Resident Evil game and a group of strange experiments.
Extreme battle mode
Complete both of either character's scenarios with an "A" rank, then go to the "Special" option. A new "Extreme battle mode" selection will be unlocked.
Getting the gatling gun
Successfully complete the game in two and a half hours or less, you can pick up items (only important things such as keys, card keys and maps recommended) but do not save. The gatling gun is an awesome weapon that shoots very fast and is powerful. The downside is that you cannot aim up or down, and it takes up two spaces on the inventory screen. When you start the next scenario in the slot you used, look in one of your item boxes.
Getting the machine gun
Play the first scenario and find the door with a small hand pad in the Umbrella Laboratory that requires two people to open. Even though you cannot get in, activate it anyway. Complete the first scenario and start the second. Find this pad again and activate it. The door will unlock and you can find a machine gun in the room.
Getting the Precinct Key
Go to the second floor, kill the Licker, and then go to the room with a door with S.T.A.R.S. written on it. Get the diary (green book), get the unicorn medal, talk to your "friend", and go down the stairs back to the fountain in the hall. Stand in front of the fountain and use the unicorn medal.
Hand gun ammunition
Always check a dead policeman. He will usually have ammunition.
Play as Ada Wong in extreme battle mode
Complete extreme battle mode level 1 as any character.
Play as Chris Redfield in extreme battle mode
Complete extreme battle mode level 2 as any character.
Play as Hunk
Complete both of either character's scenarios with an "A" rank.
Play as Tofu
Complete both of either character's scenarios with an "A" rank, and Hunk's scenario with any rank.
Ranking system
To get an A ranking, beat the game in under three hours and do not use any First Aid sprays. Herbs, however, may be used. To get a B ranking, successfully complete the game in under three hours. To get a C ranking, finish the game in five to seven hours. For a D rating, finish the game in seven hours or more. Note: The rank will be lowered by one grade if any special weapons are used, or if the game was saved more than twelve times.
To get the "S" rank on mission 1, complete the game in under 1 hour 30 minutes, only use up to one green herb, do not save, and only use a knife, handgun and shotgun/bowgun or magnum/grenade launcher. I.e., if you pick up the shotgun/bowgun do not pick up the magnum/grenade launcher; or if you want the magnum/grenade launcher, do not pick up the shotgun/bowgun. Also, no weapons upgrades are allowed on any weapon and only one of each type of weapon. I.e., do not pick up the shotgun/bowgun from the dead shopkeeper then pick it up later in the game.
Rebecca Chambers picture
Walk into the S.T.A.R.S office, go to the back of the room and click on the desk with the "This desk is trashed someone must of searched it" description. Search the desk fifty times to find a photo of Rebecca Chambers as a basketball player.
Regaining the Precinct Key
If you discarded the Precinct Key, you can regain in the room where you put the Red Jewels into the statues. Search the crates on the left side of the statue to find the it. You can also find H. Gun Ammo and an Ink Ribbon in this room.
Secret Guns
When playing Resident Evil two make sure your settings are red blood color and normal difficulty. Don't pick up any items at the start, and preserve ammo. When you get to the police station, to the side is the zombie of Brad Vickers (don't know if thats the right name). Use your handgun and kill it, a key will be dropped. This can be used in the dark room to get new costumes, however this key has another purpose. In the police station when the zombies break through the windows on the top floor, a new secret will be unlocked. Its not clear at first. In the main hall go to the left wall. There is no indication of any secrets, however, go to the middle of the wall and use the key. It will say this key is useless, but dont discard it, you'll need it to change your costumes. A doorway will open. Walk through and there is a secret lab-like room. Its very small. A conatiner is at the far end. Activate the controls and it will open. You will be given an infinite ammo magnum. If you are playing as claire first you will be given an infinite RCPD handgun that seems to be more powerful then before. When u exit, the passage willclose, and you will not be permitted to enter again unless you restart the game.
Shotgun or crossbow
When playing as Leon go to the gun shop with the man. He will almost shoot you. After he dies because of the zombies, kill them. Then go up to the dead man and press Action. You should get a shotgun. If playing as Claire you will get the crossbow.
Unlimited ammunition
Begin game play then press Start to display the options screen. Select the "Button Config." option. Highlight "Aim" then hold R and press Z(10). The white boxes around "Config" and "Aim" should change to red to confirm correct code entry.
Unlimited weapons
Complete either character's first scenario in under 2.5 hours with an A or B ranking for the special rocket launcher. Complete either character's second scenario in under 2.5 hours with an A or B ranking for the special gatling gun. Complete either character's second scenario in under 3 hours with an A or B ranking for the special machine gun. The special weapon will appear in the next game after the first chest is opened.