You can use items like rocks and logs to knock out enemies from a distance.
Once you realize where the enemies appear use stationary boots in front of the spots.
Use health regaining mushrooms wisely. That means you should avoid picking them up when you are in full health. Better to save them for when you truly need them.
It's easy to loose track of your goals so check them every now and then in game by pressing the goal icon located in the top left corner of your gameplay screen.
When hunted use evasive maneuvers to avoid running into hunter or being an easy shot if running in straight line.