| Trophy | How to unlock
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| 10 Blocks Trophy ( Bronze ) | Record 10 blocks or more with any team.
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| 10 Ranked Matches Trophy ( Silver ) | Win 10 ranked matches total.
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| 15 Steals Trophy ( Bronze ) | Record 15 steals or more with any team.
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| 15 Threes Trophy ( Bronze ) | Make 15 three pointers or more with any team.
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| 20 Ranked Matches Trophy ( Gold ) | Win 20 ranked matches total.
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| 2K Beats Playlist Trophy ( Bronze ) | Create a 2K Beats Playlist.
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| 3 Ranked Streak Trophy ( Bronze ) | Win 3 ranked matches in a row.
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| 3-for-All Trophy ( Bronze ) | Make at least 10 3pt FG's while shooting at least 45% from 3pt range with any team.
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| 30 Assists Trophy ( Bronze ) | Record 30 assists or more with any team.
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| 3pt Shootout Trophy ( Bronze ) | Win the 3pt Shootout.
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| 5 Ranked Matches Trophy ( Bronze ) | Win 5 ranked matches total.
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| 5 Ranked Streak Trophy ( Bronze ) | Win 5 ranked matches in a row.
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| All-Heart Trophy ( Bronze ) | Start the 4th period losing by 5 or more points and win the game with any team.
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| All-Hustle Trophy ( Bronze ) | Record at least 5 offensive rebounds, 5 blocks and 5 steals with any team.
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| All-NBA Trophy ( Platinum ) | Earn every trophy in NBA 2K10.
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| Brandon Roy Trophy ( Silver ) | Record at least 25 pts and 6 assts with Brandon Roy.
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| Carmelo Anthony Trophy ( Silver ) | Record at least 40 pts with Carmelo Anthony.
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| Celtics vs Lakers Trophy ( Bronze ) | User controlled team from either side must win against opponent at All-Star difficulty or higher.
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| Chris Paul Trophy ( Silver ) | Record at least 20 pts, 10 assts and 3 stls with Chris Paul.
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| Create-a-Player Trophy ( Bronze ) | Create a Player.
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| Crew Game Trophy ( Bronze ) | Win one online crew game.
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| Danny Granger Trophy ( Silver ) | Record at least 30 pts, 3 threes and 2 blks with Danny Granger.
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| Defensive FG% Trophy ( Bronze ) | Hold the opposing team's FG% below 40% with any team.
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| Deron Williams Trophy ( Silver ) | Record at least 20 pts and 12 assts with Deron Williams.
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| Dirk Nowitzki Trophy ( Silver ) | Record at least 30 pts and 8 rebs with Dirk Nowitzki.
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| Dunk-Off Trophy ( Silver ) | Defeat any challenger in a Dunk-Off.
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| Dwight Howard Trophy ( Silver ) | Record at least 20 pts, 15 rebs and 3 blks with Dwight Howard.
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| East vs West Trophy ( Bronze ) | User controlled team from either side must win against opponent at All-Star difficulty or higher.
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| G Performance Trophy ( Silver ) | Record at least 25 pts, 3 stls and 2 blks with Dwyane Wade.
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| Good Hands Trophy ( Bronze ) | Record at least 20 assists with no more than 5 turnovers with any team.
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| Ice Water Trophy ( Bronze ) | FT% over 85% with at least 10 FTA's with any team.
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| Inside Domination Trophy ( Bronze ) | Score at least 70 points in the paint with any team.
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| It's Better to Give Trophy ( Bronze ) | Share any file type through 2K Share.
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| Kevin Durant Trophy ( Silver ) | Record at least 35 pts and 6 rebs with Kevin Durant.
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| Kobe Bryant Trophy ( Silver ) | Record at least 50 pts with Kobe Bryant.
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| LeBron James Trophy ( Silver ) | Record at least 25 pts, 8 rebs, and 8 assts with LeBron James.
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| Lights Out Trophy ( Bronze ) | FG% over 60% for the game [min 40 FGA's] with any team.
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| Lockdown Trophy ( Bronze ) | Record at least 5 blocks and 5 steals with any team.
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| Pick-up Game Trophy ( Bronze ) | Win one online pick-up game.
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| Play in the NBA Trophy ( Bronze ) | Play in an NBA game in My Player.
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| Ranked Match Trophy ( Bronze ) | Win one online ranked match
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| Rebound +10 Trophy ( Bronze ) | Win the rebound battle by a margin of +10 with any team.
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| Rookie Challenge Trophy ( Bronze ) | User controlled Rookie team must beat the Sophomores at All-Star difficulty or higher.
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| Second Unit Trophy ( Bronze ) | Score at least 40 bench points with any team.
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| Sprite Slam Dunk Trophy ( Silver ) | Win the Dunk Contest using LeBron James.
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| Summer Circuit Trophy ( Bronze ) | Complete Summer Circuit in My Player.
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| Track Meet Trophy ( Bronze ) | Score at least 20 fastbreak points with any team.
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| Training Camp Trophy ( Bronze ) | Complete Training Camp in My Player.
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| Yao Ming Trophy ( Silver ) | Record at least 20 pts, 10 rebs and 3 blks with Yao Ming.
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