| Achievement | How to unlock
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| Are you okay, buddy? | Play for at least one hour with less than 20% health.
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| Better than therapy | Get fifty kills by headshots.
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| Bull in a china shop | Trigger fifty enemy alarms.
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| Clean hands | Play through the game without killing anyone, including robots and turrets.
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| Clean-O-Bot 3000 | Clean up hundred blood splatters.
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| Don't care | Step into at least thirty dangerous environmental puddles.
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| Evolutionary dead-end | Have three cloning errors at the same time.
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| Gotcha, Boomer! | Finish the game on 1999 mode difficulity.
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| Hero we deserve | Finish all the NPC side-quests.
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| Hobo for life | Finish the game without spending any money in vending machines.
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| Hygiene obsession | Clean up at least fifty blood splatters.
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| I prefer my payment in cash | Collect 2.000 credits without dying once.
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| I'm MacReady! | Finish the game on Russ Kurtell difficulity.
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| I'm all out of bubblegum | Upgrade all your weapons to the maximum.
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| Muta-Freak | Buy all the Mutamods.
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| Never there | Finish the game in "ghost mode". Never detected by any kind of enemy.
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| Not the best outcome... | Reach the "Bad" ending.
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| Out of madness | Finish the game on any difficulity.
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| Psycho-mode! | Kill at least five from every enemy type in the game, bosses not included.
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| Radio Ga Ga | Find all audio logs in the game.
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| Score! | Dump five heads into bins.
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| Space tourist | Explore all main sections of the station.
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| Squat master | Walk 5000 steps while crouching.
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| Tech-guru | Buy all the tech-gadgets.
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| The Master Exploder | Build the secret weapon!
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| The Rite | Find the way to kill Charley.
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| This is NOT the way | Finish the game in "no-hud" mode, so never use a helmet in one entire playtrough.
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| Too good to be true | Reach the "Good" ending.
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| Warren Wrenchman | Finish the game using only the Power wrench and the HyperBroom as weapons.
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