| Unlockable | How to Unlock
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|---|
| Blade E | Reach Blade Man in Easy Mode
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| Blade H | Reach Blade Man in Hard Mode
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| Blade N | Reach Blade Man in Normal Mode
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| Block Devil E | Reach Block Devil in Easy Mode
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| Block Devil H | Reach Block Devil in Hard Mode
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| Block Devil N | Reach Block Devil in Normal Mode
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| Chill E | Reach Chill Man in Easy Mode
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| Chill H | Reach Chill Man in Hard Mode
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| Chill N | Reach Chill Man in Normal Mode
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| Commando E | Reach Commando Man in Easy Mode
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| Commando H | Reach Commando Man in Hard Mode
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| Commando N | Reach Commando Man in Normal Mode
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| Crab Puncher E | Reach Crab Puncher in Easy Mode
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| Crab Puncher H | Reach Crab Puncher in Hard Mode
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| Crab Puncher N | Reach Crab Puncher in Normal Mode
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| Nitro E | Reach Nitro Man in Easy Mode
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| Nitro H | Reach Nitro Man in Hard Mode
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| Nitro N | Reach Nitro Man in Normal Mode
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| Octobulb H | Reach Octobulb (Sheep Man stage) in Hard Mode
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| Pump E | Reach Pump Man in Easy Mode
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| Pump H | Reach Pump Man in Hard Mode
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| Pump N | Reach Pump Man in Normal Mode
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| Sheep E | Reach Sheep Man in Easy Mode
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| Sheep H | Reach Sheep Man in Hard Mode
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| Sheep N | Reach Sheep Man in Normal Mode
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| Solar E | Reach Solar Man in Easy Mode
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| Solar H | Reach Solar Man in Hard Mode
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| Solar N | Reach Solar Man in Normal Mode
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| Strike E | Reach Strike Man in Easy Mode
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| Strike H | Reach Strike Man in Hard Mode
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| Strike N | Reach Strike Man in Normal Mode
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| Suzak and Fenix H | Reach Suzak and Fenix (Solar Man Stage) in Hard Mode
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| The Keeper H | Reach The Keeper Man (Strike Man Stage) in Hard Mode
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| TriCastle H | Reach TriCastle (Blade Man Stage) in Hard Mode
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| W Archive E | Reach the first Wily Archive in Easy Mode
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| W Archive H | Reach the first Wily Archive in Hard Mode
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| W Archive N | Reach the first Wily Archive in Normal Mode
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| Wily Capsule E | Reach Wily Capsule in Easy Mode
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| Wily Capsule H | Reach Wily Capsule in Hard Mode
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| Wily Capsule N | Reach Wily Capsule in Normal Mode
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| Wily Machine E | Reach Wily Machine in Easy Mode
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| Wily Machine H | Reach Wily Machine in Hard Mode
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| Wily Machine N | Reach Wily Machine in Normal Mode
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| Challenge | How to unlock
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|---|
| Blue Bomber | Beat the game in less than one hour.
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| Destroyer | Defeat 1,000 enemies.
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| Hard Rock | Reach the boss room of a stage without being damaged on the way.
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| Headbanging | Defeat all Robot Masters as a helmetless MegaMan.
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| Invincible | Beat the game without losing any lives.
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| Mr. Perfect | Beat the game without taking damage even one time.
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| No Coffee Break | Beat the game without the usage of any kind of Tank.
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| Superhero | Beat the game on Hard difficulty.
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| Tenacious | Beat the game without being forced to continue from a Game Over.
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| Trusty Sidearm | Defeat all Robot Masters without the use of special weapons.
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| Whomp Wily! | Beat the game one time.
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| World Warrior | Defeat one of all kinds of enemies.
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Note: This refers to the Challenges on Page 2: the 88 on Page 1 of the menu are those you can accept from the menu and go immediately into a specialized situation for the challenge. These must also be completed during the main story mode.